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WASHINGTON — The Biden administration is calling on people to exercise renewed caution about COVID-19, emphasizing the importance of getting booster shots for those who are eligible and wearing masks indoors as two new highly transmissible variants are spreading rapidly across the country.

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After her first marathon, Sandy Lynch set a goal to run 50 marathons by her 50th year — a feat she almost completed before the pandemic temporarily stalled her plans.

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MONTGOMERY (AP) — Testimony drew to a close Tuesday in the dueling defamation lawsuits brought by former U.S. Senate candidate Roy Moore and the woman who accused him of sexual misconduct when she was a teen.

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WASHINGTON — Pfizer on Tuesday asked the U.S. to authorize extra-low doses of its COVID-19 vaccine for children under 5, potentially opening the way for the very youngest Americans to start receiving shots as early as March.

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CLEVELAND — Native American tribes have reached settlements over the toll of opioids totaling $590 million with drugmaker Johnson & Johnson and the country's three largest drug distribution companies, according to a court filing made Tuesday.

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FLORENCE — The U.S. Food and Drug Administration's approval on Monday of the Pfizer-BioNTech COVID-19 vaccine was a much-needed move in the war against the virus, but the FDA shouldn't stop there, said Sheffield pulmonologist Dr. Lynn Ridgeway.